The nucleotide sequence of a low molecular weight ribonucleic acid from cells infected with adenovirus 2.

A low molecular weight RNA was isolated from human cells infected with adenovirus 2 and its nucleotide sequence deduced to be ,G-G-G-C-A-C-U-C-U-U-C-C-G-U-G-G-UC-U-G-G-U-G-G-A-U-A-A-A-U-U-C-G-C-A-A-G-G-G-U-AU-C-A-U-G-G-C-(G-U-G-G-A-C-G-A-C-C)-G-G-G-G-U-UC-G-A-A-C-C-C-C-G-G-A-U-C-C-G-U-G-A-U-C-C-A-U-GC-G-G-U-U-A-C-C-G-U-C-C-G-C-C-G-C-C-C-G-U-G-C-GU-C-G-A-A-C-C-C-A-G-G-U-G-U-G-C-G-A-C-G-U-C-AG-A-C-A-A-C-G-G-G-G-G-A-G-C-G-C-U-C-C-U-Uon. To determine this sequence, we analyzed the products of extensive digestion of this RNA with T, RNase, pancreatic RNase, and spleen acid ribonuclease, the products of extensive T, RNase digests of partially methylated RNA, the products of pancreatic RNase digestion of RNA modified with a water-soluble carbodiimide, the products of limited digestion of the RNA with T, RNase, and the oligonucleotides produced by spleen acid nuclease digestion of the limited T, RNase digestion products.